Table 9 Results of different network architectures on S. cerevisiae, the adopted negative dataset is constructed by NIP-SS
From: Predicting protein-protein interactions using high-quality non-interacting pairs
Architectures | Data set | ACC | PE | RE | SPE | MCC | F 1 | AUC |
|---|---|---|---|---|---|---|---|---|
DNNs | Fold 1 | 94.08% | 94.04% | 94.17% | 93.98% | 88.15% | 94.11% | 98.24% |
Fold 2 | 94.03% | 94.36% | 93.64% | 94.42% | 88.07% | 94.00% | 98.13% | |
Fold 3 | 94.57% | 95.25% | 93.66% | 95.45% | 89.14% | 94.45% | 98.17% | |
Fold 4 | 94.38% | 94.99% | 93.78% | 94.98% | 88.77% | 94.38% | 98.16% | |
Fold 5 | 94.19% | 94.84% | 93.50% | 94.88% | 88.39% | 94.17% | 98.03% | |
Average | 94.25% ± 0.22% | 94.70% ± 0.49% | 93.75% ± 0.26% | 94.74% ± 0.56% | 88.5% ± 0.45% | 94.22% ± 0.19% | 98.15% ± 0.08% | |
DNNs-Con | Fold 1 | 91.92% | 92.40% | 91.27% | 92.55% | 83.84% | 91.83% | 97.15% |
Fold 2 | 91.86% | 93.87% | 89.21% | 94.40% | 83.79% | 91.48% | 96.90% | |
Fold 3 | 91.58% | 93.62% | 89.32% | 93.86% | 83.26% | 91.42% | 96.83% | |
Fold 4 | 91.86% | 93.65% | 90.07% | 93.70% | 83.79% | 91.83% | 96.92% | |
Fold 5 | 91.42% | 92.24% | 90.53% | 92.32% | 82.86% | 91.38% | 96.93% | |
Average | 91.73% ± 0.21% ∙ | 93.16% ± 0.77% ∙ | 90.08% ± 0.86% ∙ | 93.37% ± 0.89% ∙ | 83.51% ± 0.43% ∙ | 91.59% ± 0.23% ∙ | 96.95% ± 0.12% ∙ |