Computational prediction of plasma protein binding of cyclic peptides from small molecule experimental data using sparse modeling techniques

Table 7 Descriptors and regression coefficients of the best model for cyclic peptide drugs obtained by FBS trained on small molecule training data

Descriptor	Category	Regression coef.
PEOE8	Physical property	−0.42
PEOE9	Physical property	−0.39
Xu	Topological descriptors	0.75
Percent Human Oral Absorption	Physical property	0.18
QPLogPo/w	Physical property	0.36

ISSN: 1471-2105