Table 3 Top 10 biological processes assigned to each of the selected case studies
From: Measures of co-expression for improved function prediction of long non-coding RNAs
GO ID | P-value | FDR | Term |
|---|---|---|---|
HOTAIR (development and morpogenesis) | |||
GO:0032964 | 0.00e+ 00 | 0.00e+ 00 | collagen biosynthetic process |
GO:0030199 | 1.72e-14 | 9.36e-12 | collagen fibril organization |
GO:0030198 | 1.39e-09 | 3.98e-07 | extracellular matrix organization |
GO:0007275 | 2.07e-07 | 6.27e-05 | multicellular organism development |
GO:0035115 | 5.31e-07 | 7.63e-05 | embryonic forelimb morphogenesis |
GO:0060272 | 8.21e-07 | 1.00e-04 | embryonic skeletal joint morphogenesis |
GO:0048704 | 7.01e-07 | 1.49e-04 | embryonic skeletal system morphogenesis |
GO:0001568 | 2.13e-06 | 1.88e-04 | blood vessel development |
GO:0007506 | 7.72e-06 | 1.00e-03 | gonadal mesoderm development |
GO:0002063 | 1.58e-05 | 1.01e-03 | chondrocyte development |
HCP5 (immune- and AIDS-related processes) | |||
GO:0002480 | 0.00e+ 00 | 0.00e+ 00 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent |
GO:0002504 | 0.00e+ 00 | 0.00e+ 00 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II |
GO:0002376 | 1.35e-55 | 3.37e-53 | immune system process |
GO:0050776 | 1.10e-53 | 1.22e-50 | regulation of immune response |
GO:0006955 | 6.98e-50 | 1.39e-47 | immune response |
GO:0002250 | 6.06e-28 | 1.35e-25 | adaptive immune response |
GO:0050852 | 3.56e-27 | 5.93e-25 | T cell receptor signaling pathway |
GO:0019882 | 7.67e-27 | 1.09e-24 | antigen processing and presentation |
GO:0045087 | 6.77e-23 | 1.26e-20 | innate immune response |
GO:0042110 | 8.62e-20 | 1.21e-17 | T cell activation |
HULC (liver-related processes) | |||
GO:0002933 | 0.00e+ 00 | 0.00e+ 00 | lipid hydroxylation |
GO:0006547 | 0.00e+ 00 | 0.00e+ 00 | histidine metabolic process |
GO:0006572 | 0.00e+ 00 | 0.00e+ 00 | tyrosine catabolic process |
GO:0010873 | 0.00e+ 00 | 0.00e+ 00 | positive regulation of cholesterol esterification |
GO:0010898 | 0.00e+ 00 | 0.00e+ 00 | positive regulation of triglyceride catabolic process |
GO:0016098 | 0.00e+ 00 | 0.00e+ 00 | monoterpenoid metabolic process |
GO:0030300 | 0.00e+ 00 | 0.00e+ 00 | regulation of intestinal cholesterol absorption |
GO:0034371 | 0.00e+ 00 | 0.00e+ 00 | chylomicron remodelling |
GO:0034378 | 0.00e+ 00 | 0.00e+ 00 | chylomicron assembly |
GO:0042737 | 0.00e+ 00 | 0.00e+ 00 | drug catabolic process |
H19 (cancer-related processes) | |||
GO:0007565 | 3.46e-14 | 2.79e-11 | female pregnancy |
GO:0060397 | 7.14e-08 | 1.92e-05 | JAK-STAT cascade involved in growth hormone signaling pathway |
GO:0070234 | 1.95e-06 | 3.93e-04 | positive regulation of T cell apoptotic process |
GO:0007292 | 3.90e-05 | 3.50e-03 | female gamete generation |
GO:0016486 | 3.90e-05 | 3.50e-03 | peptide hormone processing |
GO:0030325 | 3.90e-05 | 3.50e-03 | adrenal gland development |
GO:0007267 | 5.08e-05 | 4.31e-03 | cell-cell signalling |
GO:0042060 | 8.28e-05 | 5.50e-03 | wound healing |
GO:0006703 | 1.55e-04 | 8.91e-03 | estrogen biosynthetic process |
GO:0030540 | 4.66e-04 | 1.75e-02 | female genitalia development |