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Table 3 Top 10 biological processes assigned to each of the selected case studies

From: Measures of co-expression for improved function prediction of long non-coding RNAs

GO ID P-value FDR Term
HOTAIR (development and morpogenesis)
 GO:0032964 0.00e+ 00 0.00e+ 00 collagen biosynthetic process
 GO:0030199 1.72e-14 9.36e-12 collagen fibril organization
 GO:0030198 1.39e-09 3.98e-07 extracellular matrix organization
 GO:0007275 2.07e-07 6.27e-05 multicellular organism development
 GO:0035115 5.31e-07 7.63e-05 embryonic forelimb morphogenesis
 GO:0060272 8.21e-07 1.00e-04 embryonic skeletal joint morphogenesis
 GO:0048704 7.01e-07 1.49e-04 embryonic skeletal system morphogenesis
 GO:0001568 2.13e-06 1.88e-04 blood vessel development
 GO:0007506 7.72e-06 1.00e-03 gonadal mesoderm development
 GO:0002063 1.58e-05 1.01e-03 chondrocyte development
HCP5 (immune- and AIDS-related processes)
 GO:0002480 0.00e+ 00 0.00e+ 00 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
 GO:0002504 0.00e+ 00 0.00e+ 00 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
 GO:0002376 1.35e-55 3.37e-53 immune system process
 GO:0050776 1.10e-53 1.22e-50 regulation of immune response
 GO:0006955 6.98e-50 1.39e-47 immune response
 GO:0002250 6.06e-28 1.35e-25 adaptive immune response
 GO:0050852 3.56e-27 5.93e-25 T cell receptor signaling pathway
 GO:0019882 7.67e-27 1.09e-24 antigen processing and presentation
 GO:0045087 6.77e-23 1.26e-20 innate immune response
 GO:0042110 8.62e-20 1.21e-17 T cell activation
HULC (liver-related processes)
 GO:0002933 0.00e+ 00 0.00e+ 00 lipid hydroxylation
 GO:0006547 0.00e+ 00 0.00e+ 00 histidine metabolic process
 GO:0006572 0.00e+ 00 0.00e+ 00 tyrosine catabolic process
 GO:0010873 0.00e+ 00 0.00e+ 00 positive regulation of cholesterol esterification
 GO:0010898 0.00e+ 00 0.00e+ 00 positive regulation of triglyceride catabolic process
 GO:0016098 0.00e+ 00 0.00e+ 00 monoterpenoid metabolic process
 GO:0030300 0.00e+ 00 0.00e+ 00 regulation of intestinal cholesterol absorption
 GO:0034371 0.00e+ 00 0.00e+ 00 chylomicron remodelling
 GO:0034378 0.00e+ 00 0.00e+ 00 chylomicron assembly
 GO:0042737 0.00e+ 00 0.00e+ 00 drug catabolic process
H19 (cancer-related processes)
 GO:0007565 3.46e-14 2.79e-11 female pregnancy
 GO:0060397 7.14e-08 1.92e-05 JAK-STAT cascade involved in growth hormone signaling pathway
 GO:0070234 1.95e-06 3.93e-04 positive regulation of T cell apoptotic process
 GO:0007292 3.90e-05 3.50e-03 female gamete generation
 GO:0016486 3.90e-05 3.50e-03 peptide hormone processing
 GO:0030325 3.90e-05 3.50e-03 adrenal gland development
 GO:0007267 5.08e-05 4.31e-03 cell-cell signalling
 GO:0042060 8.28e-05 5.50e-03 wound healing
 GO:0006703 1.55e-04 8.91e-03 estrogen biosynthetic process
 GO:0030540 4.66e-04 1.75e-02 female genitalia development