Table 2 Properties of weighted PPIN: physical (P), functional (F) and combined (C) PPIN weighted by functional contexts: molecular function (MF), biological process (BF) or cellular components (CC)
From: Functional homogeneity and specificity of topological modules in human proteome
Network | Nodes | Edges | Avg. degree | Avg. path length | Diameter | Edge density | Clustering coeff. |
|---|---|---|---|---|---|---|---|
P-MF | 13,269 | 98,013 | 9.06 | 1.54 | 5.73 | 0.0007 | 0.133 |
P-BP | 5.25 | 0.60 | 5.13 | 0.0004 | 0.136 | ||
P-CC | 8.85 | 1.40 | 5.36 | 0.0007 | 0.135 | ||
F-MF | 11,362 | 613,865 | 43.96 | 0.42 | 4.77 | 0.0038 | 0.223 |
F-BP | 26.12 | 0.27 | 5.06 | 0.0023 | 0.222 | ||
F-CC | 46.90 | 0.64 | 5.45 | 0.0040 | 0.226 | ||
C-MF | 15,562 | 700,640 | 38.82 | 0.63 | 5.03 | 0.0025 | 0.176 |
C-BP | 22.76 | 0.28 | 4.12 | 0.0015 | 0.178 | ||
C-CC | 40.53 | 0.66 | 4.36 | 0.0026 | 0.180 |