Fig. 1

MS-Helios workflow. The construction of a circular proteome map (CPM) is a multi-step process. First, MS-Helios reads the datasets as data matrices, where the first row are sample names and the first column feature identifiers. Second, the data is processed with built-in transformation and normalization functions. Third, datasets are mapped to each other as ideogram and data tracks (light pink – missing values). In a final step, MS-Helios writes data and configuration files to construct a circular plot with Circos