Fig. 2
From: DBS: a fast and informative segmentation algorithm for DNA copy number analysis
Segmentation process with simulation data in DBS. a shows the segmentation process by splitting multiple times. Notably, DBS uses a recursive algorithm. After Node 1, 3, 4, 5, and 7 were found one by one, Node 11, etc. at right part were discovered. The red lines over gray data points is the segmentation curves. The curves are the results of segmentation, and indicate the ranges and average of each sub-segment. b shows the corresponding binary tree of ℤp generated by the left panel (a). The red dotted line represents the position of the estimated standard deviation \( \widehat{\sigma} \), and the red solid line represents the position of the threshold \( {\widehat{\sigma}}^{\prime } \) of degree of significant ℤp of breakpoints