Fig. 2From: MeDEStrand: an improved method to infer genome-wide absolute methylation levels from DNA enrichment dataIllustration of counting bin reads. A sliding bin of 100 bp divides the genome and the number of reads that fall in the bins are assigned as bin reads. Bin reads measure fragmented DNA enrichment for loci. Mapped reads include DNA strand information and are usually combined for bin counts for loci. In our method, bin reads are counted for the positive and negative DNA strands separatelyBack to article page