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Fig. 1 | BMC Bioinformatics

Fig. 1

From: NGmerge: merging paired-end reads via novel empirically-derived models of sequencing errors

Fig. 1

Analysis modes of NGmerge. The diagrams show the paired-end reads (R1, R2) derived from sequencing DNA fragments (white boxes) with sequencing adapters (gray boxes) on either end. a In the default mode (“stitch”), NGmerge combines paired-end reads that overlap into a single read that spans the full length of the original DNA fragment. b The alternative “adapter-removal” mode returns the original reads as pairs, removing the 3′ overhangs of those reads whose optimal alignment has this characteristic

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