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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Identifying genes with tri-modal association with survival and tumor grade in cancer patients

Fig. 1

Applied EM algorithm to discover trimodal genes. a A simulated example to verify the validity of the EM algorithm. b The distribution of the expression values for the gene ORMDL3 in the Metabric discovery set. c The common genes found to have trimodal distribution between the Metabric discovery set vs. Metabric validation set, and between the Metabric data and TCGA data. Hypergeometric p is given to show the significance of overlap of trimodality or non-trimodality across different cohorts of patients

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