Fig. 6

Example of pharmacokinetic fitting analysis with the presented plug-in in a glioblastoma patient using the 2CXM within the tumor ROI (red). The 4-window view shows the first time frame of the dynamic MRI series, overlaid with the parameter map of plasma flow Fp. The MFI (right) shows the measured concentration-time curve in a single voxel (red dots), together with the estimated model fit (black line) and the used AIF (green dots). The respective model parameter estimates of the fit are listed in the table below