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Fig. 3 | BMC Bioinformatics

Fig. 3

From: NCLcomparator: systematically post-screening non-co-linear transcripts (circular, trans-spliced, or fusion RNAs) identified from various detectors

Fig. 3

Variation in number of detected events and NNCL among various tools. Of note, the analysis is based on the non-ambiguous NCL events. a The coverage of identified intragenic NCL events between the compared tools (top) and the distribution of the number of supporting tools (bottom). b Boxplot representing the number of the supporting NCL-junction reads (NNCL) of the intragenic NCL events (205 events) that are identified by all nine examined circRNA detectors. c and d representing the results of intergenic NCL events identified by 6 gene-fusion detectors, related to the intragenic cases in (a) and (b), respectively. For (d), boxplot represents the 87 intergenic NCL events identified by at least two gene-fusion detectors. A zoom-in view for NNCL of SOAPfuse, ericscript, CRAC, MapSplice2, and NCLscan is shown the middle panel of (d). The identified intragenic and intergenic NCL events by various tools are listed in Additional file 2: Table S2. e Comparisons of cumulative distribution of τNCL for the non-ambiguous intragenic and intergenic NCL events. P value is determined by the Kolmogorov-Smirnov test

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