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Table 1 Simulation Design

From: Real world scenarios in rare variant association analysis: the impact of imbalance and sample size on the power in silico

Balanced Cases and Controls

Total Sample Size 20, 50, 100, 200, 400, 1000, 2000, 4000, 6000, 10,000, 14,000, 20,000

Unbalanced Cases and Controls

Number of controls 10,000

Number of controls 30,000

Number of cases

10, 25, 50, 75, 85, 100, 200, 500, 1000, 3000, 5000, 7000

Number of cases

10, 25, 50, 75, 85, 100, 200, 500, 1000