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Table 3 Detailed Parameters for Mixture Odds Ratio Design

From: Real world scenarios in rare variant association analysis: the impact of imbalance and sample size on the power in silico

 

Randomly Selected 10 Disease loci

Signal Level

OR > 1 range (Risk)

OR < 1 range (Protective)

Low

2.3

2.73

3.15

3.58

4

0.43

0.37

0.32

0.28

0.25

Moderate

4

5.25

6.5

7.75

9

0.25

0.19

0.15

0.13

0.11

High

9

11.5

14

16.4

19

0.11

0.087

0.07

0.06

0.053

  1. Note: The numbers in bold represent the boundaries when selecting the odds ratios
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BMC Bioinformatics

ISSN: 1471-2105

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