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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Exploiting locational and topological overlap model to identify modules in protein interaction networks

Fig. 1

The flowchart of module identification. For a given protein interaction network, GPIN, it is first filtered to CLPIN by the context of cell localization, and then it is imputed to form LTOPIN using both the locational and topological information. After that, ClusterONE is used to identify modules. Finally, the modules are evaluated using three functional categories, biological process, molecular function and cancer gene set. LTOM, Locational and Topological Overlap Model; Sn, Sensitivity; PPV, Positive Predictive Value; Acc, Accuracy

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BMC Bioinformatics

ISSN: 1471-2105

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