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Table 1 All predicted cTOH regions

From: Genome-wide tracts of homozygosity and exome analyses reveal repetitive elements with Barrets esophagus/esophageal adenocarcinoma risk

Chromosome regions

Length (bp)

No. of SNPs

Adjusted

P-value

Adjusted

FDR assoc.

Adjusted OR (95%CI)

1p22.3

381,139

113

0.025

0.653

4.65 (1.22,17.81)

2p23.3 - p23.2

1,363,418

165

0.021

0.888

0.32 (0.12,0.84)

3p24.3

1,039,742

238

0.015

0.315

2.78 (1.22,6.32)

3p24.3

434,675

122

0.01

0.315

8.36 (1.66,42.09)

3p24.1

628,410

100

0.023

0.315

0.21 (0.06,0.81)

3q13.32

1,263,994

227

0.028

0.315

2.67 (1.11,6.41)

4q12

434,403

115

0.034

0.625

3.89 (1.11,13.66)

4q13.1

879,986

150

0.026

0.625

0.48 (0.25,0.91)

6p12.3

1,416,850

181

0.03

0.554

0.39 (0.17,0.92)

6q14.1

384,341

102

0.039

0.554

5.3 (1.09,25.82)

7p22.2

632,597

187

0.045

0.707

2.84 (1.03,7.85)

7p12.2

462,813

129

0.031

0.707

0.34 (0.13,0.9)

8q21.11 -q21.12

1,727,694

238

0.023

0.653

2.72 (1.15,6.43)

8q22.2

1,589,641

117

0.029

0.653

0.25 (0.07,0.87)

9q21.13

1,308,361

255

0.036

0.333

0.46 (0.22,0.95)

9q21.31

491,323

107

0.026

0.333

0.25 (0.08,0.85)

9q33.1

958,487

265

0.013

0.333

2.48 (1.21,5.08)

9q34.13

367,627

107

0.037

0.333

0.18 (0.04,0.9)

12q14.1

1,242,069

168

0.038

0.611

0.37 (0.15,0.95)

13q21.1

4,413,655

608

0.002

0.05

2.38 (1.36,4.16)

14q13.3-q21.1

866,302

149

0.012

0.252

3.1 (1.28,7.49)

15q22.33-q23

1,142,927

150

0.023

0.368

4.15 (1.22,14.12)

18q12.1

584,602

124

0.004

0.052

0.15 (0.04,0.54)

20p12.1

267,272

104

0.029

0.29

4.22 (1.16,15.39)