Fig. 3

MEKK subfamily of seven plants. Orthogroup labeling is represented by colored stripes beside leaves. Significantly differentially regulated genes for Gossypium hirsutum are depicted with circles on the outer perimeter where blue circles indicate significant downregulation, red circles significant upregulation, and grey circles are not differentially regulated. Circles represent 1) cold stress, 2) heat stress, 3) drought stress, and 4) salt stress from innermost - > outermost circle. Clade A1, A3, and A5 are expansions of their previously defined clades defined by MAPK group in 2002. Clade A2 has been split into three subclades (A2–1, A2–2, and A2–3) based on orthogroup cladding. The largely expanded clade A5 (in red) is newly proposed - residing between clades A2 and A3