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Table 3 Overlapped pathways in the top 10 significant pathways found by each method in five colorectal cancer datasets (GSE4107, GSE8671, GSE9348, GSE23878, GSE4183)

From: FoPA: identifying perturbed signaling pathways in clinical conditions using formal methods

 

Overlapping Pathways in four colorectal cancer datasets

Overlapping Pathways in three colorectal cancer datasets

KEGG ID

Name

KEGG ID

Name

FoPA

04962

Vasopressin-regulated water reabsorption

04976

Bile secretion

04960

Aldosterone-regulated sodium reabsorption

04064

NF-kappa B signaling pathway

  

04978

Mineral absorption

  

05010

Alzheimer’s disease

PADOG

05210

Colorectal cancer

05211

Renal cell carcinoma

05222

Small cell lung cancer

 

CePa

04310

Wnt signaling pathway

00051

Fructose and mannose metabolism

04514

Cell adhesion molecules (CAMs)

00563

Glycosylphosphatidylinositol (GPI)-anchor biosynthesis

00430

Taurine and hypotaurine metabolism

  

04810

Regulation of actin cytoskeleton

  

04722

Neurotrophin signaling pathway

  

00250

Alanine, aspartate and glutamate metabolism

  

00983

Drug metabolism - other enzymes

  

05414

Dilated cardiomyopathy (DCM)

  

SPIA

4512

ECM-receptor interaction

3320

PPAR signaling pathway

  

4062

Chemokine signaling pathway

  

4110

Cell cycle

  

4725

Cholinergic synaps