Table 1 Comparison of existing open-source software tools with similar functions
Features | GenESysV | GEMINI | BrowseVCF | VCF-Miner | Mendel,MD | BiERapp |
|---|---|---|---|---|---|---|
Graphical Usera Interface | Yes | No | Yes | Yes | Yes | Yes |
Study type | Single cohort complex disease, Case/Control, and Mendelian inheritance | Single cohort complex disease and Mendelian inheritance | Single cohort complex and Mendelian inheritance | Single cohort complex disease and Mendelian inheritance | Mendelian only | Single cohort complex disease, Case/Control, and Mendelian inheritance |
Whole genome, exome or target study | All | All | All | All | WES or targeted study | WES or target study |
Can handle studies with large numbers of samples | Yes | Yes | No | No | No | No |
Database Type | Elasticsearch | Sqlite3 | Wormtable & BerkeleyDB | MongoDB | PostgreSQL | SQLite & MongoDB |
Flag variants for further filtering | Yes | No | No | No | No | No |