Table 2 Source and sink genes
ID | Source genes | Sink genes | # of (source, sink) combination |
|---|---|---|---|
AD | APP; CAPN1 | CASP3; APBB1; MAPT | 6 |
T2DM | INS; INSR | GLUT4 | 2 |
MEL | GF; NRAS; BRAF | CCND1; CDK4 | 6 |
PC | GF; PTEN; NKX3–1; CDKN1B | E2F1; TP53; BCL2; CASP9; BAD; FOXO1; MTOR | 28 |
ALS | SOD1 | MAP3K5; CASP3; NEFL; NEFM; NEFH | 5 |
HD | Htt; GRM5 | CASP3; ITPR1 | 4 |
PRION | PrPc | PKA | 1 |
CVID | RAG1; RAG | ICOS | 2 |
RCC | HGF; MET; EPAS1 | SLC2A1; VEGFA; TGFB1; PDGFB; GFA | 15 |
NAFLD | IL6; TNF; INS; LEP; ADIPOQ; FASLG | CASP3; CASP7; MAPK8 | 18 |