Fig. 2
FunMappOne workflow. The tool accepts as input gene lists and modification values for every experimental condition S1,…,Sn for which the enrichment will be carried out. The analysis performed on the j-th sample will results in a set of enriched terms Tsj1,…,Tsjk with an associated p-value (Enr.P) from the enrichment function applied on the gene list, or a value coming from the application of a summary statistic (SS) on the associated modification values. A matrix with n rows associated to samples and m columns associated with the enriched terms is then specified to represent the data structure beneath Level 3 representation of the data. Matrices associated to higher hierarchical levels are composed by n rows and as many columns as the categories of the level. Each cell of a higher level matrix contains a value obtained by applying SS to the terms belonging to the associated category from the Level 3 matrix