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Table 4 The predicted drug-disease associations (Top 20)

From: Prediction of drug-disease associations based on ensemble meta paths and singular value decomposition

Rank Score DrugBank ID Drug name OMIM ID Disease name Literature validation
1 0.994 DB00776 Oxcarbazepine 239350 Hyperphosphatemia, Polyuria, And Seizures [38]
2 0.992 DB01234 Dexamethasone 151590 Lichen Sclerosus Et Atrophicus; Lsa [39]
3 0.991 DB00443 Betamethasone 233810 Growth Retardation, Small And Puffy Hands And Feet, And Eczema [36]
4 0.991 DB00694 Daunorubicin 236000 Hodgkin Lymphoma [40, 41]
5 0.987 DB01234 Dexamethasone 146850 Immune Suppression; Is [42]
6 0.986 DB01013 Clobetasol propionate 233810 Growth Retardation, Small And Puffy Hands And Feet, And Eczema N.A.
7 0.986 DB00620 Triamcinolone 125600 Dermatosis Papulosa Nigra N.A.
8 0.986 DB00863 Ranitidine 600263 Helicobacter Pylori Infection, Susceptibility To [43]
9 0.985 DB00620 Triamcinolone 233810 Growth Retardation, Small And Puffy Hands And Feet, And Eczema [34, 35]
10 0.984 DB00694 Daunorubicin 267730 Reticulum Cell Sarcoma [44]
11 0.984 DB00694 Daunorubicin 109543 Leukemia, Chronic Lymphocytic, Susceptibility To, 2 N.A.
12 0.984 DB00773 Etoposide 247640 Lymphoblastic Leukemia, Acute, With Lymphomatous Features; Lall [45, 46]
13 0.984 DB00214 Torasemide 256370 Nephrotic Syndrome, Early-Onset, With Diffuse Mesangial Sclerosis N.A.
14 0.983 DB00443 Betamethasone 188030 Thrombocytopenic Purpura, Autoimmune; Aitp [47]
15 0.981 DB00444 Teniposide 601626 Leukemia, Acute Myeloid; Aml [48, 49]
16 0.981 DB00481 Raloxifene 215470 Chorioretinal Dystrophy, Spinocerebellar Ataxia, And Hypogonadotropic N.A.
17 0.980 DB00335 Atenolol 608622 Hypertension, Diastolic, Resistance To [50]
18 0.980 DB00612 Bisoprolol 608622 Hypertension, Diastolic, Resistance To [51]
19 0.980 DB00443 Betamethasone 146850 Immune Suppression; Is N.A.
20 0.980 DB01177 Idarubicin 109543 Leukemia, Chronic Lymphocytic, Susceptibility To, 2 N.A.
  1. N.A.: We haven’t found the literature evidence