Table 1 GO analysis of putative target genes of unique super-enhancer domains in lymphoblast and prefrontal cortex
Cell/tissue type | Term | Fold Enrichment |
|---|---|---|
GM12878 (Lymphoblast) | GO:0006955~immune response | 4.50 |
GO:0031295~T cell costimulation | 12.1 | |
GO:0071222~cellular response to lipopolysaccharide | 8.30 | |
GO:0000188~inactivation of MAPK activity | 22.6 | |
GO:2001244~positive regulation of intrinsic apoptotic signaling pathway | 17.2 | |
GO:0035556~intracellular signal transduction | 3.30 | |
GO:0001922~B-1 B cell homeostasis | 94.3 | |
GO:0033209~tumor necrosis factor-mediated signaling pathway | 6.40 | |
GO:0032729~positive regulation of interferon-gamma production | 12.3 | |
GO:0031532~actin cytoskeleton reorganization | 12.0 | |
Prefrontal Cortex | GO:0051965~positive regulation of synapse assembly | 21.4 |
GO:0022010~central nervous system myelination | 126 | |
GO:0007409~axonogenesis | 13.5 | |
GO:0007417~central nervous system development | 11.0 | |
GO:0031018~endocrine pancreas development | 34.0 | |
GO:0007155~cell adhesion | 3.90 | |
GO:0032570~response to progesterone | 22.7 | |
GO:0046426~negative regulation of JAK-STAT cascade | 22.1 |