Table 6 Enrichment results of trait-associated SNPs in the mediated trans-eQTLs identified in the HapMap3 data
From: Identification of trans-eQTLs using mediation analysis with multiple mediators
Population | Mediated trans-eQTL | Trait association | Enrichment p-value | |
|---|---|---|---|---|
Yes | No | |||
LWK | Yes | 2 | 11 | 0.013 |
No | 13180 | 940641 | ||
MKK | Yes | 3 | 56 | 0.055 |
No | 14365 | 975383 | ||
YRI | Yes | 2 | 53 | 0.172 |
No | 12836 | 930270 | ||
LWK+MKK+YRI | Yes | 18 | 155 | 1.484 × 10−10 |
No | 10901 | 729084 | ||
CEU | Yes | 24 | 106 | <2.2 × 10−16 |
No | 13403 | 773824 | ||
CHB+JPT | Yes | 15 | 98 | 1.019 × 10−9 |
No | 9144 | 531427 | ||