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Fig. 2 | BMC Bioinformatics

Fig. 2

From: CeModule: an integrative framework for discovering regulatory patterns from genomic data in cancer

Fig. 2

Topological features of the identified modules and the ceRNA regulatory network for ovarian cancer. a View of the ceRNA module network in OV. If two nodes are members of a module and their interactions exist in the databases as mentioned in the aforementioned interaction databases, then an edge between the two nodes is displayed. Three colors (black, purple and green) correspond to three types of interactions (lncRNA-miRNA, miRNA-gene and gene-gene). Nodes with no edges are omitted to improve visualization. b Overlap of the top 10 lncRNAs across three dimensions for OV. c The distributions of number of modules identified by CeModule for the top 10 lncRNAs, miRNAs, and mRNAs with the highest degree in OV dataset

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