From: CeModule: an integrative framework for discovering regulatory patterns from genomic data in cancer
Module | GO term | Description | q-value | Cancer lncRNAs | Cancer miRNAs | Cancer mRNAs |
---|---|---|---|---|---|---|
2 | GO:0002376 | immune system process | 1.04E-12 | MALAT1, MIR155HG, NEAT1, PVT1 | mir-10a | APOC1, APOE, BTG3, C1QA, C1QB, CBS, CCL2, etc |
GO:0009605 | response to external stimulus | 2.31E-07 | ||||
GO:0006954 | inflammatory response | 2.76E-04 | ||||
GO:0050865 | regulation of cell activation | 2.25E-03 | ||||
GO:0007154 | cell communication | 2.25E-03 | ||||
7 | GO:0032502 | developmental process | 1.32E-06 | DLEU2, DNM3OS, GAS5, HOTAIRM1, MALAT1, SNHG1, SNHG3, SNHG5, TP53TG1 | mir-196b, mir-199b | CHST2,CLDN11,COX6B1, MGP, DACT3, DCHS1, DLK1, etc |
GO:0030154 | cell differentiation | 1.62E-05 | ||||
GO:0060284 | regulation of cell development | 1.06E-04 | ||||
GO:0010942 | positive regulation of cell death | 2.89E-04 | ||||
GO:0007275 | multicellular organismal development | 7.77E-07 | ||||
15 | GO:0007155 | cell adhesion | 2.57E-06 | GAS5, H19, MEG3, SNHG5 | mir-202, mir-506, mir-508, mir-513c | FSTL1, LHX1, MEST, MFAP2, CDH3, NR5A1, MMP2, etc |
GO:0022610 | biological adhesion | 2.64E-06 | ||||
GO:0009968 | negative regulation of signal transduction | 1.38E-03 | ||||
GO:0042698 | ovulation cycle | 3.10E-04 | ||||
GO:0050896 | response to stimulus | 2.54E-05 | ||||
17 | GO:0022411 | cellular component disassembly | 1.43E-20 | DNM3OS, GAS5, H19, LINC00467, MEG3, RMRP, RP11-304 L19.5, RP11-385 J1.2, SNHG5 | mir-127,mir-134,mir-379, mir-370,mir-382,mir-409, mir-410, mir-431, mir-432, mir-433,mir-485, mir-493, mir-654, mir-758 | GPC3, SPARC, LHX1, LUM, MEST, MFAP2, IGF2BP2, etc |
GO:0009968 | negative regulation of signal transduction | 7.65E-04 | ||||
GO:0060284 | regulation of cell development | 8.80E-04 | ||||
GO:0045595 | regulation of cell differentiation | 5.91E-04 | ||||
GO:0006413 | translational initiation | 8.31E-21 |