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Fig. 3 | BMC Bioinformatics

Fig. 3

From: InTAD: chromosome conformation guided analysis of enhancer target genes

Fig. 3

a Comparison of the number of enhancer associated genes obtained when considering IMR90 TADs compared to randomly generated TADs. The number of significantly correlated enhancer associated genes (EAGs) is constantly higher throughout the tested range of adjusted p-values when accessing the original TADs compared to random TADs. Error bars indicate standard deviation in the results of the 100 random sets of TADs. b EAGs annotated by both, InTAD and the “closest gene” approaches, are compared to each other across a varying range of the closest genes (2–10, x-axis). The mutual agreement of both approaches is shown on the y-axis as a covered fraction of detected enhancer associated genes from the results of the other approach

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