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Fig. 4 | BMC Bioinformatics

Fig. 4

From: InTAD: chromosome conformation guided analysis of enhancer target genes

Fig. 4

a Venn-diagram showing the number and overlap of enhancer associated genes identified in our original study compared to the re-analysis of the same data using InTAD by also considering genes located outside of TADs. b The transcription factor SOX10 is specifically active in ependymoma tumors of the subtype PF-EPN-A and significantly correlated with an enhancer element located 40,275 bp upstream of the SOX10 transcription start site. SOX10 was missed previously, because it is located outside of TADs obtained from IMR90 cells and was therefore not considered during the enhancer-gene correlation analysis

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