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Table 2 Several miRNAs are significantly enriched in functions or diseases related to BRCA

From: Identifying miRNA-mRNA regulatory relationships in breast cancer with invariant causal prediction

miRNAs

Functions or diseases associated with BRCA

Enriched terms

hsa-miR-187-5p

regulation of mononuclear cell migration

GO:0071675

hsa-miR-205-5p

negative regulation of cell fate commitment

GO:0010454

 

regulation of cell fate specification

GO:0042659

 

mesodermal cell fate specification

GO:0007501

 

endodermal cell fate commitment

GO:0001711

 

mesodermal cell fate commitment

GO:0001710

 

Sporadic Breast Carcinoma

umls:C1336076

hsa-miR-196a-5p

Rap1 signalling pathway

hsa04015

hsa-miR-5683

negative regulation of mesenchymal cell apoptotic

GO:2001054

 

regulation of mesenchymal cell apoptotic process

GO:2001053

 

mesenchymal cell apoptotic process

GO:0097152

 

endodermal cell fate commitment

GO:0001711

 

regulation of neural precursor cell proliferation

GO:2000177

hsa-miR-363-5p

mononuclear cell migration

GO:0071674

 

positive regulation of mononuclear cell migration

GO:0071677

 

epidermal cell differentiation

GO:0009913

 

IL-17 signalling pathway

hsa04657

hsa-miR-577

Sporadic Breast Carcinoma

umls:C1336076

hsa-miR-135b-5p

Inflammatory Breast Carcinoma

umls:C0278601

hsa-miR-1247-5p

epidermal cell differentiation

GO:0009913

hsa-miR-202-5p

IL-17 signalling pathway

hsa04657