PanRV: Pangenome-reverse vaccinology approach for identifications of potential vaccine candidates in microbial pangenome

Table 2 Comparison of PanRV with other available tools on the basis of selected features

Features	Vaxign	NERVE	Jenner-predict	VacSol	PanRV
Pangenome Estimation	×	×	×	×	✓
Protein Localization Prediction	✓	✓	✓	✓	✓
Essential Genes Identification	×	×	×	✓	✓
Virulent Factor Identification	×	✓	✓	✓	✓
Homology Analysis with Human	✓	✓	✓	✓	✓
Homology Analysis with Gut Flora	✓	✓	✓	×	✓
Identification of Trans Membrane Helices	✓	✓	✓	✓	✓
Molecular Weight Estimation	×	×	×	×	✓
Epitope Mapping	✓	×	✓	✓	✓
Functional Annotation using COG	×	×	×	×	✓
Antibiotic Resistance Association Analysis	×	×	×	×	✓
Graphical User Interface	✓	×	✓	✓	✓
Downloadable Package	×	✓	×	✓	✓
Automatic Installer	×	×	×	✓	✓

× indicates absence while ✓ indicates the presence of a specific feature in the respective tools