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Table 3 List of vaccine targets prioritized via PanRV

From: PanRV: Pangenome-reverse vaccinology approach for identifications of potential vaccine candidates in microbial pangenome

RVM

ARM

FAM

PanRV ID

Candidate Proteins (COG)

No. B cell Epitope

No. T cell Epitope

Resistance Association

COG ID

Function (UniProt)/annotation

95

Surface antigen

4

9

COG3942 M

ssaA2_1

169

LysM repeat

3

6

COG1388 M

N-acetylmuramoyl-L-alanine amidase sle1alanine amidase sle1

262

phosphomethylpyrimidine kinase

2

2

COG0351 H

Putative pyridoxine kinase

323

LysM repeat

5

6

COG1388 M

Probable autolysin SsaALP

998

Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain

2

2

COG0265 O

Serine protease Do-like HtrA

1303

Surface antigen

3

5

COG3942 M

Staphylococcal secretory antigen ssaA2_2

1306

Surface antigen

4

5

COG3942 M

Staphylococcal secretory antigen ssaA2_3

  1. RVM (Reverse Vaccinology Module) results include PanRV IDs of 7 prioritized proteins along with the protein names and number of B and T cell epitopes. The results of ARM (Antibiotic Resistance Association Module) are illustrated as ARO IDs (if any) and the FAM (Functional Annotation Module) results are shown as COG IDs along with their functional annotations retrieved from UniProt