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Fig. 3 | BMC Bioinformatics

Fig. 3

From: DSab-origin: a novel IGHD sensitive VDJ mapping method and its application on antibody response after influenza vaccination

Fig. 3

Characters of B cell repertoire before and after influenza vaccination. a Percentage changes of IGHV gene usage. Red line represents the changes in ASCs after vaccination with naive B cells as background, while the blue line represents the changes in ABCs under the same condition. b Percentage changes of IGHD gene usage. Red line represents the changes in ASCs after vaccination with naive B cells as background. Blue line represents the changes in ABCs. c VDJ gene recombination usage in ASCs among three donors. The purple diamonds represent each donor, and points represent each VDJ gene recombination. The size of points represents the expression level changes in ASCs with naive B cells as background. Red points represent the combinations with top 3 expression level in each donor, while others are blue. The lines represent that which donor the combination belongs to. d VDJ gene recombination usage in ABCs among three donors. The purple diamonds represent each donor, and points represent each VDJ gene recombination. The size of points represents the expression level changes in ABCs with naive B cells as background. Red points represent the combinations with top 3 expression level in each donor, while others are blue. The lines represent that which donor the combination belongs to

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BMC Bioinformatics

ISSN: 1471-2105

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