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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Haplin power analysis: a software module for power and sample size calculations in genetic association analyses of family triads and unrelated controls

Fig. 2

Power analysis using the Haplin function hapPowerAsymp. a Child effects for varying numbers of case-parent triads, using a MAF of 0.2; b Child effects for varying values of MAFs, using a total of 500 case-parent triads; c PoO effects for varying numbers of case-parent triads, using a MAF of 0.2; d PoO effects for varying values of MAFs, using a total of 500 case-parent triads. For the PoO effects, RRF=1, so that the value of RRM/RRF is equal to RRM. A nominal significance level of 0.05 was used throughout. The power was calculated at relative risks/relative risk ratios of 1,1.05,1.10,…,2. Intermediate values correspond to line segments joining two adjacent points

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