Table 2 Partial conclusions from the inference of TFs regulation were verified by gene functional enrichment analysis
Conclusions | Pathways | P-values, upside* | P-values, downside* | Regulation |
|---|---|---|---|---|
Enhance insulin sensitivity Promote adipogenesis Attenuate hyperlipidemia | PPAR signaling pathway (KEGG) | 3.98e-8 | ≈1 | ↑ |
Peroxisome (KEGG) | 4.62e-11 | ≈1 | ||
peroxisome organization | 2.99e-4 | ≈1 | ||
Promote fatty acid metabolism | fatty acid metabolism (KEGG) | 1.86e-9 | ≈1 | ↑ |
cellular lipid metabolic process (GO) | 3.49e-7 | ≈1 | ||
long-chain fatty acid metabolic process (GO) | 9.54e-6 | ≈1 | ||
very long-chain fatty acid metabolic process (GO) | 6.73e-5 | ≈1 | ||
regulation of fatty acid oxidation (GO) | 5.30e-4 | ≈1 | ||
fatty acid beta-oxidation (GO) | 1.17e-5 | ≈1 | ||
Inhibit angiogenesis | blood vessel development (GO) | 0.996 | 3.72e-3 | ↓ |
Reduce inflammation | intestinal immune network for IgA production (KEGG) | 0.995 | 5.32e-3 | ↓ |