Skip to main content
Fig. 7 | BMC Bioinformatics

Fig. 7

From: Multiscale modeling reveals angiogenesis-induced drug resistance in brain tumors and predicts a synergistic drug combination targeting EGFR and VEGFR pathways

Fig. 7

Spatial distributions of drugs and microenvironmental factors. a, b Spatial distributions of concentrations of EGFRI (a) and VEGFRI (b) at the end of the simulation (450 h). c-f Spatial distributions of different microenvironmental factors under the combined treatment of VEGFRI and EGFRI at the end of the simulation (450 h). VEGFRI was added at 240 h. c Glucose. d TGFα. e Oxygen. f VEGF

Back to article page