Table 4 Functional enrichment of KEGG pathways for part of DNB
Term | Description | Genes | p-value |
|---|---|---|---|
hsa04640 | Hematopoietic cell lineage | CD3G, CD8A, CD3D, CD3E, IL7R, FLT3LG, CD1D, IL4R, MS4A1, CD2, CD5, CD14, HLA-DRA | 3.23E-11 |
hsa04060 | Cytokine-cytokine receptor interaction | IFNAR2, TNFRSF1B, IL2RB, TNFSF10, IL18RAP, CCR5, IL4R, CCR1, TGFBR2, CXCR1, IL7R, CD27, IL17RA, FLT3LG | 3.87E-07 |
hsa04210 | Apoptosis | TNFSF10, NTRK1, RIPK1, FADD, CAPN2, PIK3R2 | 3.82E-04 |
hsa05220 | Chronic myeloid leukemia | BCR, TGFBR2, ABL1, CRK, PIK3R2 | 0.005920 |
hsa04010 | MAPK signaling pathway | DUSP4, RASGRP1, NTRK1, MAP3K1, TGFBR2, CRK, CD14 | 0.043672 |
hsa04151 | PI3K-Akt signaling pathway | FGFR2, IFNAR2, IL2RB, CD19, IL4R, RXRA, ITGB7, PIK3CD, RAC1, JAK3, IL7R, PIK3R2 | 0.059021 |