L2,1-GRMF: an improved graph regularized matrix factorization method to predict drug-target interactions

BMC Bioinformatics

Table 3 AUPR Results for Interaction Prediction Under CVt

Methods	NR	GPCR	IC	E
CMF	0.379(0.020)	0.540(0.028)	0.751(0.014)	0.740(0.014)
GRMF	0.423(0.032)	0.567(0.027)	0.745(0.008)	0.763(0.020)
WGRMF	0.423(0.017)	0.574(0.027)	0.801(0.008)	0.801(0.018)
L₂₁-GRMF	0.465(0.056)	0.607(0.020)	0.823(0.012)	0.804(0.021)
L_2,1-WGRMF	0.425(0.023)	0.603(0.026)	0.801(0.007)	0.802(0.016)
WKNKN+CMF	0.434(0.029)	0.557(0.021)	0.742(0.015)	0.772(0.014)
WKNKN+GRMF	0.500(0.028)	0.615(0.023)	0.815(0.010)	0.807(0.016)
WKNKN+WGRMF	0.446(0.015)	0.585(0.027)	0.799(0.007)	0.798(0.018)
WKNKN+L_2,1-GRMF	0.519(0.038)	0.617(0.024)	0.826(0.008)	0.799(0.016)
WKNKN+L_2,1-WGRMF	0.457(0.032)	0.548(0.021)	0.799(0.012)	0.791(0.014)

ISSN: 1471-2105