Combining gene ontology with deep neural networks to enhance the clustering of single cell RNA-Seq data

BMC Bioinformatics

Table 8 Highly ranked GO-term nodes for some cell types used for traing GOAE and GONN models

Model	Cell type	GO term	GO function
GOAE	ES	GO:0043008	ATP-dependent protein binding [37]
	ES	GO:0032409	Regulation of transporter activity [37]
GONN	ES	GO:0022417	Protein maturation by protein folding [37]
	ES	GO:0140101	Catalytic activity, acting on a tRNA [37]
	BMDC	GO:0099590	Neurotransmitter receptor internalization [40]
	BMDC	GO:0050881	Musculoskeletal movement [40]
	Zygote	GO:0001892	Embryonic placenta development [38]
	Early 2cell	GO:0032552	Deoxyribonucleotide binding [41]

ISSN: 1471-2105