Fig. 4

Agreement for predictions of homologous protein pairs. 95% of all pairs of homologous proteins agreed to a score ≥ 0.5 (Eq. 5); 74% reached full agreement (score = 1; black lines in A and B). a If both proteins were predicted using the same approach (either homology-based inference or de novo), the fraction of agreement was very similar. Predictions disagreed more when the proteins were predicted by different approaches. b Predictions for yeast proteins and homologs in any other organism disagreed more than for other pairs of organisms