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Fig. 3 | BMC Bioinformatics

Fig. 3

From: pwrEWAS: a user-friendly tool for comprehensive power estimation for epigenome wide association studies (EWAS)

Fig. 3

Empirical assessment of the number of simulations. To assess the number of simulated data sets (number of simulations) required to obtain consistent results for power, pwrEWAS was run for a variety of number of simulations (5–100 simulations), each 100 times and each with the same remaining input parameters. a shows the distribution of power estimates for 100 runs within each of the assumed number of simulations. b visualizes the variance of power estimates for each of the assumed number of simulations. Given the relative stability of variance estimates beyond 50 simulations, 50 was selected as the default value for the number of simulations in pwrEWAS

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