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Table 4 Prediction results of ten drug compounds

From: Computational determination of hERG-related cardiotoxicity of drug candidates

Name In vivo result   Prediction
  Our model Pred-hERG binary Pred-hERG multiclass OCHEM Predictora
Haloperidol Toxic Toxic Toxic Nontoxic Nontoxic
Cimetidine Nontoxic Nontoxic Toxic Nontoxic Nontoxic
Disopyramide Toxic Toxic Nontoxic Nontoxic Nontoxic
Quinnidine Toxic Nontoxic Toxic Nontoxic Toxic
Terazosin Nontoxic Nontoxic Toxic Nontoxic Nontoxic
Spironolactone Nontoxic Nontoxic Toxic Nontoxic Nontoxic
Sotalol Toxic Nontoxic Nontoxic Nontoxic Nontoxic
Cefazoline Nontoxic Nontoxic Toxic Nontoxic Nontoxic
Chloropromazine Toxic Toxic Toxic Toxic Nontoxic
Loratadine Nontoxic Nontoxic Toxic Nontoxic Nontoxic
  1. aConsensus II in the predictor was used