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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Tree reconciliation combined with subsampling improves large scale inference of orthologous group hierarchies

Fig. 1

Hierarchical orthologous groups and the consistency problem. Letters represent species while the subscript number of each letter represents a gene of the relative species. Boxes and circles represent orthologous groups (OG), while the number inside the circle denotes the number of genes in the respective OG. The example shows how genes are clustered into OGs based on the chosen taxonomic level (dotted line) and how the independently computed levels can be joined into a hierarchy of OGs(right side). a shows a hierarchically inconsistent definition, while b shows the repaired and consistent definition. The presented consistency pipeline acts with split and merge operations to make the network consistent are highlighted in orange. (Figure based on [40])

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