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Table 1 Descriptive statistics of the T2D studies, datasets, and results used in this study. The letter code shows the population from which the samples were obtained, Significant tagSNPs shows the number of tagSNPs that were found to be significantly associated with T2D at the significance threshold applied by the corresponding study (also shown in the table). Significant tagSNPs+LD shows the total number of these significant SNPs and the number of SNPs that are in linkage disequilibrium with these SNPs, but were not screened by the corresponding study

From: Cross-population analysis for functional characterization of type II diabetes variants

Populations

# Cases

# Controls

# Screened SNPs

# Significant tagSNPs

Significance Threshold (P-value)

# Significant tagSNPs + LD

British (W)

1,999

1,504

495,477

482

< 1e −5

1,831

American + European (D)

1,007

983

561,656

350

< 1e −8

1,686

Finnish (F)

1,161

1,174

317,503

157

<  5 x1e − 7

898

French (Fr)

679

697

392,365

4

<  7 × 1e −4

71

Saudi (S)

2,207

2,276

48

41

<  0.05

297

Korean (K)

462

456

2,188,613

395

< 1e −5

1,859

Japanese (J)

23,399

31,722

7,521,072

211

< 1e −8

668

Chinese (C)

684

955

2,900,000

33

<  2.6 x 1e−8

361

Lebanese (L)

1,902

1,384

5,891,794

23

< 1e −5

61