Table 1 Comparison of different partition strategies and complexities
Strategy I | Strategy II | Strategy III | ||
|---|---|---|---|---|
ODE | Reactions | Protein diffusion | Protein diffusion, catalytic reaction | Diffusion, reactions involving proteins |
System Size | 50 × 8 equations | 50 × 8 equations | 50 × 37 equations | |
SSA | Reactions | mRNA diffusion, all 141 reactions | mRNA diffusion, rest 140 reactions | mRNA diffusion, synthesis, degradation |
Firing Interval | 1e−6 | 2e−5 | 6 e−5 | |
Running Time of HR hybrid Method | 9.5h | 1h | 4h | |