Fig. 3
From: In silico modeling of phosphorylation dependent and independent c-Myc degradation
The results obtained from the two models. a The signal pulse of of Model 1 with respect to time; b The overall population of c-Myc in Model 1 with respect to time; c The signal pulse and overall c-myc population of Model 2 with respect to time. a The three signals Erk, GSK3β and FBXW7 in the phosphorylation dependent Model 1 with respect to time is given. Erk is denoted in red, Gsk3β in green and FBXW7 in blue. b The graph represents levels of c-Myc of the phosphorylation dependent model in all four states (x1, x2, x3 and x4) along with total myc concentration (xT) with respect to time. The colour coding is given alongside the graph. c The signal pulse in phosphorylation independent Model 2, where signal pulse Skp2 is given. In addition, the two states of c-Myc, x1 and x4 with respect to time is given in the same graph. The colour coding is given alongside the graph