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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Quantification of experimentally induced nucleotide conversions in high-throughput sequencing datasets

Fig. 4

Single-Nucleotide Polymorphism masking: a ROC curves for three unlabeled mESC replicates (−4SU) vs three labeled replicates (+4SU) across variant fractions from 0 to 1 in steps of 0.1. b Log10 relative errors of simulated T > C vs recovered T > C conversions for naïve (red) and SNP-masked (blue) datasets for nucleotide-conversion rates of 2.4 and 7%. c Barcodeplot of 3′ intervals ranked by their T > C read count including SNP induced T > C conversions. Black bars indicate 3′ intervals containing genuine SNPs. d Barcodeplot of 3′ intervals ranked by their T > C read count ignoring SNP masked T > C conversions

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BMC Bioinformatics

ISSN: 1471-2105

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