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Table 2 Proportion of realizations with p < 0.05 for ES, ESavg, and < ESavg > for 25 splits. The proportion was calculated over 100 realizations of the dataset for each of the 21 gene sets using the 3 test statistics, ES, ESavg, and < ESavg > with M = 25. a indicates a control gene set with no association with phenotype

From: Improving the power of gene set enrichment analyses

Gene Set Proportion with p < 0.05
ES ESavg <ESavg>
a a 0.06 0.08 0.05
b 1.00 1.00 1.00
c 0.82 0.81 0.92
d 0.09 0.09 0.14
e 0.38 0.39 0.46
f 0.06 0.13 0.10
g 0.01 0.00 0.01
h 0.29 0.19 0.19
i 0.10 0.16 0.07
j a 0.07 0.07 0.07
k 0.92 0.93 0.98
l 0.81 0.88 0.91
m 0.92 0.94 0.98
n 0.34 0.35 0.43
o 0.73 0.76 0.84
p 0.42 0.56 0.64
q 0.77 0.84 0.90
r 0.22 0.26 0.22
s 0.75 0.77 0.90
t 0.36 0.38 0.44
u 0.25 0.28 0.37