Fig. 11
From: Balancing sensitivity and specificity in distinguishing TCR groups by CDR sequence similarity
Pathology specificity of McPAS-TCR repertoires. For each pair of pathologies in a set of size-matched repertroies (7 small, 6 large), 1-nearest-neighbor classification was performed to predict whether a CDR was correlated with one pathology or the other. Each sub-plot summarizes the performance of such as classification test for one such pair of pathologies (row vs. column). The bars indicate the percentage of correct (blue), incorrect (magenta), and unidentified (green) predictions between a pair of pathologies (row and column) at thresholds of 0.2, 0.3, and 0.4