Fig. 6
From: Balancing sensitivity and specificity in distinguishing TCR groups by CDR sequence similarity
Example twin motifs with different specificity patterns. Motifs represent sequences for four different clusters from subject A1, and the closest clusters to each of those in each of the five other individuals. The x-axis indicates the distance from the A1 cluster to a cluster from another individual, assessed as the average over pairs of CDRs. Sets of clusters illustrate different types of patterns: (common) all of the clusters are similar to the cluster from A1 (within 0.3); (twin-distinct) clusters from unrelated individuals are closer than that from the twin; (twin-specific) the twin’s cluster is closer than those from other individuals; (A1-specific) the cluster is far from all clusters from all other individuals