Fig. 7
From: Balancing sensitivity and specificity in distinguishing TCR groups by CDR sequence similarity
Epitope specificity in Dash et al. repertoires. The plots track the performance of nearest-neighbor classification, using sequence similarity to predict a CDR’s epitope from a set of seven different murine epitopes or from a set of three different human ones. As the threshold required to make a classification is increased (x-axis), the fraction of sequences (y-axis) that are unclassified (green line) decreases, trading off the fraction that are correctly (blue line) vs. incorrectly (magenta) classified