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Fig. 2 | BMC Bioinformatics

Fig. 2

From: anamiR: integrated analysis of MicroRNA and gene expression profiling

Fig. 2

The proposed workflows in the anamiR package. (a) The general workflow provides six steps including normalization (optional), differential expression analysis, conversion of miRNA names (optional), correlation analysis, database intersection, and functional analysis. miRNA-gene interaction pairs and correspondingly enriched pathways can be identified from the workflow using both mRNA and miRNA expression data. (b) The function-driven analysis workflow is performed to identify significantly dysregulated pathways and to obtain potential miRNA-gene interaction pairs using genome-wide expression profiles. Each box shown in blue represents a function in the anamiR package. The input data and output results are shown in green. Yellow cylinders indicate databases for query and numbers of dataset collections are shown in parentheses

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